원발성 전립성 미만성 대세포 B 림프종
Primary Diffuse Large Q-cell Lymphoma of the Prostate
김동철, 이아원, 강창석, 박경신, 한경자,
소속 상세정보
김동철 ( Kim Dong-Chul )
가톨릭대학교 의과대학 임상병리학교실
이아원 ( Lee Ah-Won )
가톨릭대학교 의과대학 임상병리학교실
강창석 ( Kang Chang-Suk )
가톨릭대학교 의과대학 임상병리학교실
박경신 ( Park Gyeong-Sin )
가톨릭대학교 의과대학 임상병리학교실
한경자 ( Han Kyung-Ja )
가톨릭대학교 의과대학 임상병리학교실
KMID : 0357920030370060432
Abstract
Primary lymphomas of the prostate are extremely rare and can mimic other more common prostatic lesions clinically. We report a case of primary diffuse large B-cell lymphoma of the prostate in an 81-year-old man. The patient presented with voiding difficulty as an initial symptom and enlargement of the prostate on rectal digital examination. Transurethral prostatic resestion was performed. On microscopic examintion, atypicaly lymphoid cells infittrated and replaced the prostatic parenchyma. The tumor cells had large nuclei with irregular nuclear membrane and vesicular clumped chromatin. Nucleoli were not distinct and the cells had scanty cytoplasm. Immunohistochemically, the tumor cells were immunoreactive for CD20 and CD79a but not reactive for CD5, BCL-2 and BCL-6. Histopathological diagnosis was diffuse large B-cell lymphoma of the prostate. The patient received 5 cycles of chemotherapy after histologic diagnosis but died from pulmonary and scrotal metastases 6 months later.
키워드
Prostate-Lymphoma;Large Cell;Diffuse
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