Down Syndrome Associated with Testicular Seminoma
김나래, 정재걸, 조현이,
소속 상세정보
김나래 ( Kim Na-Rae )
가천의대 길병원 병리과
정재걸 ( Chung Jae-Gul )
가천의대 길병원 병리과
조현이 ( Cho Hyun-Yee )
가천의대 길병원 병리과
KMID : 0357920030370060442
Abstract
Individuals with Down syndrome have a suscepfibility to neoplastic transformation, increased risk of chronic leukemia and central nervous system tumors. Recently, an increased number of cases of testicular germ cell tumors have been reported in individuals with Down syndrome, with more than forty cases in the literature. Here we report the first Korean case of seminoma with Down syndrome, in a 190year-old institutionalized man who presented with painfu scrotal swelling. Percutaneous needle biopsy showed histology of seminoma with invasion to the adjacent epididymis. Both testes were orthotopic. He underwent orchiectomy of the affected side, and the surgical staging was stage I seminoma with complete resection. We emphasize that the physician and nursing staff should be aware of the increased incidence of testicular seminoma in Down syndrome, because testicular seminoma might be mislnterpreted as a scrotal infection with subsequent needle biopsy, which is contraindicated to avoid possible lymphatic metastasis.
키워드
Down syndrome;Seminoma;Testicular Tumor;Infection
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