An Unusual Type of Acute Renal Failure due to Extensive Crystal Deposition in the Renal Tubular Epithelium and Interstitium - A Case Report -
구자승, 정현주, 강신욱, 신은아,
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구자승 ( Koo Ja-Seung )
연세대학교 의과대학 병리학교실
정현주 ( Jeong Hyeon-Joo )
연세대학교 의과대학 병리학교실
강신욱 ( Kang Shin-Wook )
연세대학교 의과대학 내과학교실
신은아 ( Shin Eun-Ah )
연세대학교 의과대학 병리학교실
KMID : 0357920040380050337
Abstract
Acute tubular necrosis is a major cause of acute renal failure. Acute renal failure that is caused by crystal deposition can result from drug toxicity, lymphoplasmacytic neoplasms, ingestion of industrial organic solvents, or intratubular obstruction due to degenerated red blood cells and red blood cell casts. We herein present an uncommon case of acute renal failure in a 57-year-old woman showing an unusually massive accumulation of variable-sized, round, ellipsoid or rhomboid, pale-pink, refractile bodies in the proximal and distal tubular epithelial cells, interstitial macrophages and Bowman´s spaces. These bodies were electron dense with a maximum diameter of 3 m. The information we gathered from the patient history, the laboratory data and the various histochemical and immunohistochemical analyses failed to reveal the exact nature of these crystal-like structures.
키워드
Kidney Failure;Acute;Kidney Tubular Necrosis;Acute;Crystal;like structures
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