Diffuse Leiomyomatosis of the Uterus -A Brief Case Report-
김수진, 노미숙,
소속 상세정보
김수진 ( Kim Soo-Jin )
동아대학교 의과대학 병리학교실
노미숙 ( Roh Mee-Sook )
동아대학교 의과대학 병리학교실
KMID : 0357920050390010063
Abstract
Diffuse leiomyomatosis of the uterus is a rare condition that is distinguished from the uterine leiomyoma due to the diffuse involvement of the myometrium by numerous, ill-defined, smooth muscle nodules. We present here a case of diffuse uterine leiomyomatosis in a 34-year-old woman. The hysterectomy revealed a symmetrically enlarged uterus containing numerous, small, ill-defined leiomyomatous nodules. Microscopically, the nodules were composed of compact fascicles and interweaving bundles of uniform benign smooth muscle cells. On the immunohistochemical staining, the progesterone receptor level was higher in the leiomyomatosis than in the adjacent normal myometrial tissue, but the estrogen receptor level and Ki-67 labeling index were equal in both areas. At the twelve months follow-up, this patient has been doing very well with no evidence of pelvic or intraabdominal recurrence of disease.
키워드
Leiomyomatosis;leiomyoma;Ki-67;sex steroid receptor;Uterus
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