Juvenile Xanthogranuloma of the Nasal Cavity - A Case Report and Review of the Literature -
안준석, 이주한, 이응석, 김영식, 한선희, 박흠례,
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안준석 ( An Jung-Suk )
고려대학교 의과대학 안산병원 병리학교실
이주한 ( Lee Ju-Han )
고려대학교 의과대학 안산병원 병리학교실
이응석 ( Lee Eung-Seok )
고려대학교 의과대학 안산병원 병리학교실
김영식 ( Kim Young-Sik )
고려대학교 의과대학 안산병원 병리학교실
한선희 ( Han Sun-Hee )
고려대학교 의과대학 안산병원 병리학교실
박흠례 ( Park Heum-Rye )
고려대학교 의과대학 안산병원 병리학교실
KMID : 0357920060400030241
Abstract
Juvenile xanthogranuloma (JXG) is a benign and self-limiting non-Langerhans-cell histiocytosis that generally occurs during infancy and childhood. It develops frequently in the head and neck but is very rare in the nasal cavity. To date, only five cases of JXG in the nasal cavity have been reported. Here, we report the second case of JXG in the nasal cavity in Korea. A 19-year-old male patient presented with a protruding 1.1 cm mass in the left nasal vestibule. Histologically, a dense dermal infiltrate of histiocytes with Touton giant cells was observed. Immunohistochemically, the histiocytes tested positive for CD68 and the S-100 protein but negative for CD1a. This shows that a S-100-positive histiocytic lesion dose not exclude a diagnosis of JXG.
키워드
Juvenile xanthogranuloma;Nasal cavity;Langerhans-cell histiocytosis
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