크론병에서 위 내시경 생검의 병리 소견
Pathological Findings of Crohn’s Disease in the Stomach
유창영, 최규용, 김경미, 권기영, 이보인, 박철근, 강창석, 맹이소, 이안희,
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유창영 ( Yoo Chang-Young )
가톨릭대학교 의과대학 병원병리학교실
최규용 ( Choi Gyu-Yong )
가톨릭대학교 의과대학 내과학교실
김경미 ( Kim Kyoung-Mee )
성균관대학교 의과대학 삼성서울병원 병리학교실
권기영 ( Kwon Ghee-Young )
성균관대학교 의과대학 삼성서울병원 병리학교실
이보인 ( Lee Bo-In )
가톨릭대학교 의과대학 내과학교실
박철근 ( Park Cheol-Keun )
성균관대학교 의과대학 삼성서울병원 병리학교실
강창석 ( Kang Chang-Suk )
가톨릭대학교 의과대학 병원병리학교실
맹이소 ( Maeng Lee-So )
가톨릭대학교 의과대학 병원병리학교실
이안희 ( Lee An-Hi )
가톨릭대학교 의과대학 병원병리학교실
KMID : 0357920060400040269
Abstract
Background: The incidence of Crohn‘s disease in the upper digestive tract, and especially in the stomach, is recently increasing. Focal inflammatory reaction without Helicobacter pylori (H. pylori) infection is thought to be the characteristic pathologic findings suggesting Crohn’s disease in the stomach. Yet gastric involvement of Crohn’s disease has not been studied in Korea. We studied the endoscopic and pathologic findings of patients with Crohn’s disease in the stomach by taking biopsies.
Methods: Thirty patients with Crohn’s disease who underwent gastroduodenoscopy followed by biopsies were included in the study. The pathology of the gastric biopsy specimens and the presence of H. pylori were evaluated.
Results: Among 30 cases, 22 cases (73.3%) were H. pylori negative and 8 cases (26.7%) were H. pylori positive. For the H. pylori negative cases, all but one cases showed pit abscess and focal lymphocytic collections in the antrum. Granulomas were found in 6 cases (20%) and they were exclusively located in the antrum.
Conclusions: In the stomach, pit abscess and focal lymphocytic collections that are not associated with H. pylori infection are the characteristic pathologic findings found in Crohn’s disease.
키워드
Crohn’s disease;Lymphocytes collection;Granuloma;Helicobacter pylori
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