Ectopic Hamartomatous Thymoma - A Case Report along with a Review of the Literature Concerning the Histogenesis and New Nomenclature -
석상희, 강수환, 배영경, 이동현,
소속 상세정보
석상희 ( Seok Sang-Hee )
영남대학교 의과대학 병리학교실
강수환 ( Kang Soo-Hwan )
영남대학교 의과대학 외과학교실
배영경 ( Bae Young-Kyung )
영남대학교 의과대학 병리학교실
이동현 ( Lee Dong-Hyun )
영남대학교 의과대학 외과학교실
KMID : 0357920060400040292
Abstract
Ectopic hamartomatous thymoma (EHT) is a rare and distinctive benign neoplasm of the lower neck. We here report on a case of EHT arising in the suprasternal area of 47-year-old male patient. The well-circumscribed mass measured 7×6×4 cm and it predominantly had a solid gray-white cut surface. Microscopically, the tumor consisted of spindle cells, epithelial nests, and mature adipose tissue. The epithelial component was arranged in anastomosing cords, solid nests and variable-sized cysts that were lined by squamous or cuboidal epithelium. The spindle cells revealed the myoepithelial immunohistochemical phenotype. There was no obvious thymic differentiation nor was any normal thymic tissue observed in our case. We think that EHT needs to be reclassified with using different nomenclature to designate its origin and histology. Further, pathologists and clinicians should be aware of the existence of this tumor in the lower neck so as not to mistake it for high-grade sarcoma or spindle cell carcinoma.
키워드
Thymoma;Hamartoma;Branchial arch;Mixed tumor;Immunohistochemistry
원문 및 링크아웃 정보
등재저널 정보