Undifferentiated Carcinoma Arising in a Choledochal Cyst - A Case Report -
이희은, 현창림, 이유정, 설혜실, 장자준,
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이희은 ( Lee Hee-Eun )
서울대학교 의과대학 병리학교실
현창림 ( Hyun Chang-Lim )
서울대학교 의과대학 병리학교실
이유정 ( Lee You-Jeong )
서울대학교 의과대학 병리학교실
설혜실 ( Seol Hye-Sil )
서울대학교 의과대학 병리학교실
장자준 ( Jang Ja-June )
서울대학교 의과대학 병리학교실
KMID : 0357920060400060461
Abstract
An association between choledochal cyst and carcinoma is well established. Here, we report an extremely rare case of undifferentiated carcinoma exhibiting extensive sarcomatous features arising in a choledochal cyst. The patient in our case had a radiologically confirmed cho- ledochal cyst and anomalous pancreaticobiliary ductal union, and mild wall thickening in the cyst was observed on endoscopic retrograde cholangiopancreatography. The patient underwent common bile duct excision and cholecystectomy. In the choledochal cyst, a nodule measuring 1.5×1 cm was detected. The lesion was composed of atypical, spindle-shaped and large, round pleomorphic tumor cells simulating sarcoma. Neither glandular nor squamous differentiation was observed. These cells were immunoreactive for both vimentin and cytokeratin by immunohistochemistry. These histologic and immunohistochemical findings were consistent with undifferentiated carcinoma, spindle and giant cell type, according to the WHO classification.
키워드
Choledochal cyst;Common bile duct;Carcinoma;Neoplasm
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