Intraneural Perineurioma in the Tongue - A Case Report -
강준, 강신광, 최진, 김정원, 서을주, 이부규, 유은실,
소속 상세정보
강준 ( Kang Jun )
울산대학교 의과대학 서울아산병원 병리과
강신광 ( Khang Shin-Kwang )
울산대학교 의과대학 서울아산병원 병리과
최진 ( Choi Jene )
울산대학교 의과대학 서울아산병원 병리과
김정원 ( Kim Jeong-Won )
울산대학교 의과대학 서울아산병원 병리과
서을주 ( Seo Eul-Ju )
울산대학교 의과대학 서울아산병원 진단검사의학과
이부규 ( Lee Bu-Kyu )
울산대학교 의과대학 서울아산병원 치과학교실
유은실 ( Yu Eun-Sil )
울산대학교 의과대학 서울아산병원 병리과
KMID : 0357920070410010051
Abstract
We report a case of an intraneural perineurioma that developed in an unusual location, the tongue. A 16-year-old male presented with a 1 cm sized protruding submucosal mass in his tongue without any sensory or motor signs or symptoms. The mass was excised. The mucosa was intact, with an ill-defined firm mass measuring 1.0×0.8×0.6 cm in the submucosa and muscle. The cut surface of the mass was pinkish gray and fibrotic. Microscopically, the mass contained tortuous and thickened peripheral nerve bundles in the submucosa, showing onion bulb like structures. The onion bulb like structures consisted of centrally located S-100 protein positive Schwann cells surrounded by Glut-1 positive perineurial cells. The FISH study did not reveal any genetic aberrations in chromosome 22.
키워드
Nerve sheath neoplasms; Tongue neoplasms; Immunohistochemistry; In situ hybridization; Fluorescence; Genes; Neurofibromatosis 2
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