태아수종의 원인: 149부검례 분석
Causes of Hydrops Fetalis: Analysis of 149 Autopsy Cases
이호창, 지제근, 박성혜,
소속 상세정보
이호창 ( Lee Ho-Chang )
서울대학교 의과대학 병리학교실
지제근 ( Chi Je-Geun )
서울대학교 의과대학 병리학교실
박성혜 ( Park Sung-Hye )
서울대학교 의과대학 병리학교실
KMID : 0357920070410020103
Abstract
Background: Hydrops fetalis is defined as abnormal accumulation of serous fluid in two or more fetal compartments, and this malady is known to be associated with various pathologic conditions.
Methods: We collected 149 cases of hydrops fetalis out of 2,312 autopsies, and we tried to elaborate the underlying causes of hydrops fetalis. The diagnosis was based on the material from either antenatal termination or intrauterine death.
Results: The relative incidence of hydrops fetalis was 6.44% of all the pediatric autopsies we performed. The gestational age was evenly distributed from 18 to 33 weeks, except for 30 to 31 weeks. There was no sex difference in the incidence of hydrops fetalis. The main causes were cardiovascular diseases (30.9%), cystic hygroma (13.4%), chromosomal anomaly (8.05%), thoracic conditions (7.38%), followed by urinary tract malformation (4.03%), infection (4.03%) and anemia (3.36%). The most common chromosomal anomaly was Turner syndrome and the second one was Down syndrome.
Conclusion: Since various conditions can be the cause of hydrops fetalis, pathologists should pay attention to elaborate the underlying causes in every single autopsy.
키워드
Autopsy; Fetus; Hydrops fetalis
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