Sclerosing Mucoepidermoid Carcinoma of the Parotid Gland - A Case Report -
김현철, 이주한, 이응석, 권순영, 김택군, 김영식,
소속 상세정보
김현철 ( Kim Hyun-Chul )
고려대학교 의과대학 안산병원 병리학교실
이주한 ( Lee Ju-Han )
고려대학교 의과대학 안산병원 병리학교실
이응석 ( Lee Eung-Seok )
고려대학교 의과대학 안산병원 병리학교실
권순영 ( Kwon Soon-Young )
고려대학교 의과대학 안산병원 이비인후-두경부외과학교실
김택군 ( Kim Taik-Kun )
고려대학교 의과대학 안산병원 진단방사선학교실
김영식 ( Kim Young-Sik )
고려대학교 의과대학 안산병원 병리학교실
KMID : 0357920070410030193
Abstract
Sclerosing mucoepidermoid carcinoma (SMEC) is a very rare tumor of the salivary gland. There have been eight cases of SMEC reported in the medical literature; this is the first reported case in Korea. A 51-year-old woman presented with a right infra-auricular mass that she had for 3 years. We performed superficial parotidectomy. Grossly, the resected parotid gland showed a well-circumscribed firm mass. Histologically, the tumor consisted of central solid or ductal tumor nests within a dense fibrous stroma surrounded by peripheral lymphoid infiltration. The tumor nests were composed of squamous, intermediate and mucin-secreting cells. However, the tumor cells lacked mitosis and nuclear anaplasia. The lymphoid cells were mostly composed of lymphocytes and plasma cells with occasional eosinophils and neutrophils. Im- munohistochemically, the tumor cells were positive for high- and low- molecular weight cytokeratins, cytokeratin 7, p16INK4A, Bcl-2 and cyclin D1. The patient also underwent radiation therapy. We report here on a case of SMEC of the parotid gland along with the immunohistochemical characteristics, and we review the relevant literature.
키워드
Mucoepidermoid carcinoma;Sclerosis;Parotid gland
원문 및 링크아웃 정보
등재저널 정보