Nasal Chondromesenchymal Hamartoma - A Case Report -
강준, 안긍환, 차희정, 최혜정, 홍영옥, 김영민,
소속 상세정보
강준 ( Kang Jun )
울산대학교 의과대학 서울아산병원 병리과
안긍환 ( Ahn Geung-hwan )
성균관대학교 의과대학 삼성서울병원 병리학교실
차희정 ( Cha Hee-Jung )
울산대학교병원 병리과
최혜정 ( Choi Hye-Jeong )
울산대학교병원 병리과
홍영옥 ( Hong Young-Ok )
울산대학교 의과대학 서울아산병원 병리과
김영민 ( Kim Young-Min )
울산대학교병원 병리과
KMID : 0357920070410040258
Abstract
We report a case of nasal chondromesenchymal hamartoma. A 14-year-old boy presented with a 5 cm sized mass in the left maxillary sinus, facial swelling and a loose tooth. A subtotal left maxillectomy with a bone graft was performed. The excised mass was composed of partly encapsulated, solid and cystic fragments of soft tissues. The mass contained chondroid and myxoid areas consisting of mesenchymal tissues including hyaline cartilage, osteoid and spindle cells in various proportions. The hyaline cartilage component was the most prominent. The spindle cell component had a fibrous matrix with variable myxoid or sclerotic changes. Thick hyalinized eosinophilic osteoid-like trabeculae were focally present. Immunohistochemically, all the mesenchymal cells tested positive for vimentin. The chondrocytes tested positive for the S-100 protein, and the spindle cell component showed focal immunoreactivity for smooth muscle actin and desmin. However, the cells were negative to pan-cytokeratin and p63.
키워드
Nose neoplasm;Hamartoma;Adolescent;Aneurysmal bone cyst;Immunohistochemistry
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