모낭모세포종에서 유래한 모낭모세포성 암종 - 1예 보고 -
Trichoblastic Carcinoma arising in Trichoblastoma - A Case Report -
서경진, 이교영, 정지한, 유진영, 강석진, 이혜경,
소속 상세정보
서경진 ( Seo Kyung-Jin )
가톨릭대학교 의과대학 임상병리학교실
이교영 ( Lee Kyo-Young )
가톨릭대학교 의과대학 임상병리학교실
정지한 ( Jung Ji-Han )
가톨릭대학교 의과대학 임상병리학교실
유진영 ( Yoo Jin-Young )
가톨릭대학교 의과대학 임상병리학교실
강석진 ( Kang Seok-Jin )
가톨릭대학교 의과대학 임상병리학교실
이혜경 ( Lee Hye-Kyung )
가톨릭대학교 의과대학 임상병리학교실
KMID : 0357920070410040274
Abstract
Trichoblastic carcinoma is a rare malignant neoplasm of follicular germ cell origin; to the best of our knowledge, only six trichoblastic carcinomas arising in trichoblastomas have appeared on the literature. We recently experienced a trichoblastic carcinoma arising in a long standing trichoblastoma. A 68-year old woman came to the hospital with a chief complaint of an ulcerated nodule on her face. The nodule, 1.1×0.9 cm with an asymmetrical configuration, had been present and unchanged for more than 20 years, however, it grew suddenly with painful burning sensation. An excisional biopsy was performed and disclosed a deeply invasive, highgrade carcinoma, which consisted of cohesive epithelial cells arranged in irregular plump or germinative cell nests of various sizes. However, at the periphery of the tumor was a benign
trichoblastoma surrounded by perifollicular sheath. We believe that the present case is a trichoblastic carcinoma developed via malignant transformation of pre-existing trichoblastoma.
키워드
Skin;Hair follicle;Tumor
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