Adenocarcinoma Arising from Heterotopic Gastric Mucosa in Cervical Esophagus - A Case Report -
홍영옥, 박승일, 이인철, 이진혁, 황정은, 조경자,
소속 상세정보
홍영옥 ( Hong Young-Ok )
울산대학교 의과대학 서울아산병원 병리과
박승일 ( Park Seung-Il )
울산대학교 의과대학 서울아산병원 흉부외과
이인철 ( Lee In-Chul )
울산대학교 의과대학 병리학교실
이진혁 ( Lee Gin-Hyug )
울산대학교 의과대학 서울아산병원 내과학교실
황정은 ( Hwang Jeong-Eun )
울산대학교 의과대학 서울아산병원 병리과
조경자 ( Cho Kyung-Ja )
울산대학교 의과대학 서울아산병원 병리과
KMID : 0357920080420010033
Abstract
Heterotopic gastric mucosa (HGM) of the upper esophagus, referred as "cervical inlet patch (CIP)", is a benign lesion that is present in 3.8-10% of the adult population. Adenocarcinomas arising from HGM of the upper esophagus are exceedingly rare. The authors report one additional case of histologically confirmed adenocarcinoma arising from a CIP. The patient had concomitant primary adenocarcinoma of the colon. The right hemicolectomy specimen and total esophagectomy specimen after preoperative chemoradiotherapy showed histologically different adenocarcinomas. The residual esophageal tumor was characterized by large mucin pools, fibrous septa, and floating tumor cells. HGM of both the fundic and antral types was seen on the surface and sides of the tumor. The independent origins of the two cancers were confirmed by immunohistochemical studies for cytokeratins 7 and 20. Without further treatment, the patient remained free of disease after 29 months of follow-up.
키워드
Esophageal neoplasm; Heterotopic tissue; Adenocarcinoma
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