Gliosarcoma with Components of Anaplastic Oligodendroglioma and Unclassifiable Spindle Cells - A Case Report-
최정우, 원남희, 안준석, 정용구, 채양석, 이영석,
소속 상세정보
최정우 ( Choi Jung-Woo )
고려대학교 의과대학 해부병리과학교실
원남희 ( Won Nam-Hee )
고려대학교 의과대학 병리과학교실
안준석 ( An Jung-Suk )
고려대학교 의과대학 병리학교실
정용구 ( Chung Yong-Ku )
고려대학교 의과대학 신경외과학교실
채양석 ( Chae Yang-Seok )
고려대학교 의과대학 병리학교실
이영석 ( Lee Young-Seok )
고려대학교 의과대학 병리학교실
KMID : 0357920080420010045
Abstract
Gliosarcoma is a distinct disease entity that is characterized by a biphasic tissue pattern with alternating areas displaying glial and mesenchymal differentiation. The tumor in our case was a rare morphologic variant of gliosarcoma with components of anaplastic oligodendroglioma and unclassifiable spindle cells. Spindle cells showed CD34 and S-100 protein immunoreactivity, which was possibly related to peripheral nerve sheath differentiation. This unique feature has not been described previously and so this case expands the spectrum of possible divergent mesenchymal differentiation, and it lends support to pluripotential stem cells being the origin of this tumor.
키워드
Gliosarcoma; Anaplastic oligodendroglioma; CD34; S-100 protein
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