Mucinous Tubular and Spindle Cell Carcinoma of Kidney Occurring in a Patient with Pulmonary Adenocarcinoma
박석연, 정진수, 이강현, 강경훈, Ro Jae Y, 박원서, 홍은경, Jennifer Black,
소속 상세정보
박석연 ( Park Seog-Yun )
서울대학교 의과대학 병리학교실
정진수 ( Chung Jin-soo )
국립암센터 비뇨기과
이강현 ( Lee Kang-Hyun )
국립암센터 비뇨기과
강경훈 ( Kang Gyeong-Hoon )
서울대학교 의과대학 병리학교실
( Ro Jae Y )
USA The Methodist Hospital Department of Pathology
박원서 ( Park Weon-Seo )
국립암센터 연구소
홍은경 ( Hong Eun-Kyung )
국립암센터 연구소
( Jennifer Black )
Weill Medical College of Cornell University
KMID : 0357920080420010054
Abstract
Mucinous tubular and spindle cell carcinoma (MTSCC) is a rare type of kidney tumor that has only been recently described. Furthermore, a case of MTSCC associated with a simultaneous lung cancer in the same patient has never been reported in the literature. In this paper, we describe a kidney tumor that was detected during staging work-up in a 72-year-old lung cancer patient. The kidney tumor was removed and shown to exhibit histological and immunophenotypic features of MTSCC, completely distinct from the pulmonary adenocarcinoma. In addition, this case was unique because it was characterized by neuroendocrine differentiation as well as p53 and Ki-67 overexpression in tumor cells. Therefore, we report a case of MTSCC diagnosed in a patient with pulmonary adenocarcinoma and describe the detailed histologic and immunohistochemical features of MTSCC.
키워드
Spindle cell carcinoma; Kidney neoplasm; Lung cancer; Multiple primary neoplasm
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