Brown Bowel Syndrome that Developed after Total Gastrectomy - A Case Report -
이선아, 김현경, 배지윤, 강한나, 정하린, 정혜경, 조민선,
소속 상세정보
이선아 ( Lee Sun-Ah )
이화여자대학교 의과대학 병리학교실
김현경 ( Kim Hyung-Kyung )
이화여자대학교 의과대학 병리학교실
배지윤 ( Bae Ji-Yoon )
이화여자대학교 의과대학 병리학교실
강한나 ( Kang Han-Na )
이화여자대학교 의과대학 병리학교실
정하린 ( Cheong Ha-Rin )
이화여자대학교 의과대학 병리학교실
정혜경 ( Jung Hye-Kyung )
이화여자대학교 의과대학 내과학교실
조민선 ( Cho Min-Sun )
이화여자대학교 의과대학 병리학교실
KMID : 0357920080420030165
Abstract
The brown bowel syndrome (BBS) is an uncommon disorder, which is characterized by brown pigmentation of the intestine due to the accumulation of lipofuscin in the smooth muscle cells. Vitamin E deficiency has generally been considered as the cause of this malady. BBS has been reported in a wide variety of malabsorptive diseases involving the pancreas, liver and gastrointestinal tract. We report here on a case of brown bowel syndrome that occurred in a 73-year-old man who had undergone total gastrectomy 11 years ago for gastric adenocarcinoma. He has complained about intestinal obstructive symptoms for several years, and these symptoms were recently aggravated. He showed a low serum concentration of total protein, albumin and cholesterol, and he had been treated for megaloblastic anemia due to vitamin B12 and folate deficiency several months ago. The resected small bowel showed lipofuscin deposition in the muscle layer of the intestine and large vessels. The electron microscopic examination revealed multiple electron dense lipofuscin deposits with irregular shapes and sizes in the cytoplasm.
키워드
Lipofuscin; Ceroid; Enteropathy; Postgastrectomy syndrome
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