Carcinosarcoma (True Malignant Mixed Tumor) of the Parotid Gland - A Report of a Case with Small Cell Carcinoma as the Carcinoma Component -
김헌수, Cho Hyang-Jung, 정연태, 박순아, 조해중, 김진만,
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김헌수 ( Kim Hun-Soo )
충남대학교 의과대학 병리학교실
( Cho Hyang-Jung )
충남대학교 의과대학 병리학교실
정연태 ( Chung Yeun-Tai )
원광대학교 의과대학
박순아 ( Park Soon-Ah )
원광대학교 의과대학 핵의학교실
조해중 ( Cho Hae-Joong )
원광대학교 의과대학 산부인과학교실
김진만 ( Kim Jin-Man )
충남대학교 암공동연구소
KMID : 0357920080420030175
Abstract
True malignant mixed tumor (carcinosarcoma) of the salivary gland is an extremely rare tumor. By definition, it is a heterologous neoplasm that’’s composed of both malignant epithelial and mesenchymal components. We report here on a case of an 83 year old female patient with a parotid gland mass. Histologic examination showed a biphasic pattern of growth with both a poorly differentiated epithelial component and a sarcomatous spindle cell background. The immunohistochemical and ultrastructural findings support the diagnosis of a small cell neuroendocrine epithelial tumor and an undifferentiated malignant mesenchymal features. The histologic and ultrastructural features along with the immunohistochemical findings are presented. We also review the literature and we discuss the different opinions on the exact histogenesis of the true malignant mixed tumor of the salivary gland. To the best of our knowledge, this histological pattern has not been previously reported in the English medical literature.
키워드
Carcinosarcoma; Parotid gland; Carcinoma; small cell; Immunohistochemistry;Microscopy; electron
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