갑상샘에서 발생한 부신경절종 - 1예 보고 -
Paraganglioma of the Thyroid - A Case Report -
백진주, 이연수, 이교영, 강창석, 심상인,
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백진주 ( Baek Jin-Joo )
가톨릭대학교 의과대학 병원병리학교실
이연수 ( Lee Youn-Soo )
가톨릭대학교 의과대학 병원병리학교실
이교영 ( Lee Kyo-Young )
가톨릭대학교 의과대학 병원병리학교실
강창석 ( Kang Chang-Suk )
가톨릭대학교 의과대학 병원병리학교실
심상인 ( Shim Sang-In )
가톨릭대학교 의과대학 병원병리학교실
KMID : 0357920080420060401
Abstract
Paragangliomas (PGs) of the thyroid are very rare tumors. Based on the medical literature, thyroid PGs invariably affected women and they were always thought to be benign, and they have always been mistaken for other more common lesions. We report here on the first case of PG of the thyroid in a 45-year-old man in Korea. Ultrasonographically, the tumor showed hypoechoic features. Microscopically, the tumor showed the typical zellballen pattern. The small to medium-sized tumor cells contained moderate amounts of finely granular eosinophilic cytoplasm and round to oval nuclei with fine chromatin. The tumor invaded the thyroid capsule and the extrathyroidal tissue with vascular and perineural invasion. Immunohistochemically, the tumor showed positivity for chromogranin, S-100 protein, CD56a, and synaptophysin and negativity for calcitonin, thyroglobulin, galectin-3, p53, CK19, and EMA. The Ki-67 labeling Index was 10%. We concluded that our case has a high potential of metastasis, and a close follow up would be important.
키워드
Thyroid; Paraganglioma
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