현미경적 대장염; 24명 환자에서의 병리학적 고찰
Microscopic Colitis: The Pathologic Features of 24 Korean
이선아, 강민정, 정성애, 구혜수,
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이선아 ( Lee Sun-Ah )
이화여자대학교 의학전문대학원 병리학교실
강민정 ( Kang Min-Jung )
이화여자대학교 의학전문대학원 내과학교실
정성애 ( Jung Sung-Ae )
이화여자대학교 의학전문대학원 내과학교실
구혜수 ( Koo Hae-Soo )
이화여자대학교 의학전문대학원 병리학교실
KMID : 0357920090430020133
Abstract
Background: The clinical presentation of microscopic colitis (MC) consists of chronic non-bloody watery diarrhea for weeks or months at a time, abdominal pain, and changes in bowel habits with a normal mucosal appearance upon performing colonoscopy. MC includes two relatively well established histopathologic entities: collagenous colitis (CC) and lymphocytic colitis (LC) as well as atypical forms. The recognition of the microscopic findings of this heterogeneous entity is very important for making the correct diagnosis and providing proper treatment.
Methods: We studied the colonoscopic biopsy specimens that were obtained from 26 patients who had clinical findings that were suggestive of MC.
Results: Fifteen patients (M: F=9:6) and 9 patients (M:F=5:4) showed the microscopic features of LC and MC, not otherwise specified, respectively.
Conclusions: The clinicopathologic findings (the incidence of the subtypes, the patients` ages and the male/female ratio) of the 24 cases of MC in this study showed differences from the previously reported findings from other countries. Further studies with a sufficient number of patients from multi-centers would be necessary to confirm the regional or ethnic influence.
키워드
Microscopic colitis;Lymphocytic colitis;Collagenous colitis;Lymphocyte count;
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