The Cytologic Features of Desmoplastic Small Round Cell Tumor with Intranuclear Inclusions - A Case Report -
이호창, 한혜숙, 이옥준,
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이호창 ( Lee Ho-Chang )
충북대학교 의과대학 병리학교실
한혜숙 ( Han Hye-Sook )
Chungbuk National University
이옥준 ( Lee Ok-Jun )
충북대학교 의과대학 병리학교실
KMID : 0357920090430030279
Abstract
Desmoplastic small round cell tumor (DSRCT) is a rare neoplasm of young adults and it is characterized by polyphenotypic differentiation. We experienced a case of abdominal DSRCT that occurred in a 19-year-old female who presented with painful swelling of her right forearm. The tumor was cytokeratin-negative and it exhibited some tumor cells with intranuclear inclusions. Molecular demonstration of EWS-WT1 fusion transcripts is particularly useful to confirm the diagnosis of DSRCT without epithelial differentiation. We report here on a case of cytokeratin-negative DSRCT that showed an unusual feature of intranuclear inclusions.
키워드
Desmoplastic small round cell tumor;Cytokeratin;EWS-WT1 fusion protein;Intranuclear Inclusions;Cytology
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