Omental Histiocytic Sarcoma - A Case Report -
한상학, Kim Song-Chul, 류민희, 박찬정, 허주령,
소속 상세정보
한상학 ( Han Sang-Hak )
울산대학교 의과대학 서울아산병원 병리과
( Kim Song-Chul )
울산대학교 의과대학 서울아산병원 일반외과
류민희 ( Ryu Min-Hee )
울산대학교 의과대학 서울아산병원 내과학교실
박찬정 ( Park Chan-Jeong )
울산대학교 의과대학 서울아산병원 임상병리학과
허주령 ( Huh Joo-Ryung )
울산대학교 의과대학 서울아산병원 병리과
KMID : 0357920090430040351
Abstract
We report a case of perigastric histiocytic sarcoma (HS) involving the lesser omental sac in a 30-year-old man. HS is an exceedingly rare malignancy of mature tissue histiocyte. The tumor was a multi-lobulated, bulging enhancing mass in the lesser omentum with metastasis to lymph nodes and liver. The tumor consisted of diffuse non-cohesive proliferation of pleomorphic large oval to round neoplastic cells with giant cells showing vesicular chromatin and ample eosinophilic cytoplasm. In some areas, the tumor cells showed spindling with elongation of the nuclei and cellular shapes. Many of the tumor cells, especially giant forms contained phagocytosed lymphocytes. Immunohistochemical analysis of the tumor cells showed expression of leukocyte common antigen, CD68, lysozyme, vimentin, CD4, and CD163. Ki-67 index was 50-60%. After the operation, he was treated with chemotherapy, but the response was poor.
키워드
Sarcoma;Histiocytic sarcoma;Omentum
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