Eosinophilic Fasciitis Associated with Overlying Intraepidermal Blister Formation - A Case Report -
김나래, 정동해, 하승연,
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김나래 ( Kim Na-Rai )
가천의과학대학교 길병원 병리과학교실
정동해 ( Chung Dong-Hae )
가천의과학대학교 길병원 병리학교실
하승연 ( Ha Seung-Yeon )
가천의과학대학교 길병원 병리과학교실
KMID : 0357920090430050478
Abstract
Eosinophilic fasciitis is a scleroderma-like disease and it may present with paraneoplastic syndrome or as an isolated form of the disease. We report here on a case of eosinophilic fasciitis in a 20-year-old woman who presented with an abrupt onset of subcutaneous limb swelling and peripheral eosinophilia. Pathologically, the specimen was characterized by acute inflammation and thickening of the collagen bundles in the reticular dermis and superficial muscle fascia in addition to the overlying intraepidermal blisters that contained many eosinophils. Eosinophils, some lymphocytes and plasma cells were infiltrated in the superficial muscle fascia and subcutaneous fat. The diagnosis of eosinophilic fasciitis was confirmed by biopsy. It is intriguing that eosinophilic fasciitis showed the microscopic findings of intraepidermal blister with predominant inflammation, and the patient showed a good response to steroid therapy.
키워드
Eosinophilia;Fasciitis;Panniculitis;Blister
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