Hepatoid Thymic Carcinoma - A Case Report -
이정현, 김현철, 채양석, 원남희, 최종상, 김철환,
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이정현 ( Lee Jeong-Hyeon )
고려대학교 안암병원 병리과
김현철 ( Kim Hyun-Chul )
고려대학교 안암병원 병리과
채양석 ( Chae Yang-Seok )
고려대학교 안암병원 병리과
원남희 ( Won Nam-Hee )
고려대학교 안암병원 병리과
최종상 ( Choi Jong-Sang )
고려대학교 안암병원 병리과
김철환 ( Kim Chul-Hwan )
고려대학교 안암병원 병리과
KMID : 0357920090430060562
Abstract
We report here on a rare case of hepatoid thymic carcinoma in a 34-year-old man. The patient complained of a high fever and headache, and a 6.6cm-sized anterior mediastinal mass was found on chest computed tomography (CT). There was no hepatic mass seen on abdominal CT. The resected mass consisted of epithelioid cells with abundant eosinophilic cytoplasm, pleomorphic vesicular nuclei and prominent nucleoli, and the mass was surrounded by thymic tissue. The tumor cells were immunopositive for cytokeratin 7, α-1-antitrypsin, hepatocyte staining, and epithelial membrane antigen, but they were negative for CD5, α-fetoprotein (AFP) and placental alkaline phosphatase, and this all led to a diagnosis of hepatoid thymic carcinoma rather than hepatoid yolk sac tumor. This entity should be included in the differential diagnosis of epithelioid thymic tumors.
키워드
Thymus;Thymus neoplasms;Carcinoma;hepatocellular
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