Cytology of Follicular Dendritic Cell Sarcoma on Intraoperative Touch Imprint Smears - A Case Report -
송주영, 한지영, 김루시아, 박인서, 김준미, 주영채, 최석진, 최석진,
소속 상세정보
송주영 ( Song Ju-Young )
인하대학교병원 병리과학교실
한지영 ( Han Jee-Young )
인하대학교 의과대학 병리학교실
김루시아 ( Kim Lucia )
인하대학교병원 병리과학교실
박인서 ( Park In-Suh )
인하대학교병원 병리과학교실
김준미 ( Kim Joon-Mee )
인하대학교 의과대학 병리학교실
주영채 ( Joo Young-Chae )
인하대학교병원 병리과학교실
최석진 ( Choi Suk-Jin )
인하대학교 의과대학 병리학교실
최석진 ( Choi Suk-Jin )
동국대학교 의과대학 해부병리학교실
KMID : 0357920090430060589
Abstract
Follicular dendritic cell (FDC) sarcoma is a neoplastic proliferation of FDCs. Because its cytologic findings can vary widely, both the cytomorphology and histopathology of FDC sarcoma can impose a significant diagnostic dilemma. We present cytologic features of FDC sarcoma assessed by intraoperative touch imprint. Intra-abdominal lymphadenopathies were noted in 54-year-old male with hepatitis B-virus associated liver cirrhosis. In contrast to cytologic features of classical FDC sarcoma, the tumor cells featured a large epithelioid or Reed-Sternberg cell-like shape scattered in a background with abundant inflammatory cells, which led to a mistaken diagnosis of malignant lymphoma. However, in accordance with cytologic features previously described in the literature, the tumor cells were characterized by a fragile cytoplasm with cytoplasmic processes in dendritic or reticulated patterns reminiscent of the ultrastructural features of FDC. Cytoplasmic features rendering nuclei with a tendency to form clusters or syncytial aggregates associated with reactive lymphocytes appear to be the most valuable finding in diagnosis of FDC sarcoma.
키워드
Dendritic cell;Follicular;Sarcoma;Cytology;Lymph nodes
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