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Fine Needle Aspiration Cytology of Langerhans Cell Histiocytosis of Mandible - A Case Report -

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ÀÌ»ó·É ( Lee Sang-Ryung ) 
¿ï»ê´ëÇб³ ÀÇ°ú´ëÇÐ ¼­¿ï¾Æ»êº´¿ø º´¸®Çб³½Ç

¼­ÀçÈñ ( Suh Jae-Hee ) 
¿ï»ê´ëÇб³ ÀÇ°ú´ëÇÐ ¿ï»ê´ëÇб³º´¿ø º´¸®Çб³½Ç
Â÷ÈñÁ¤ ( Cha Hee-Jung ) 
¿ï»ê´ëÇб³º´¿ø º´¸®°ú
±è¿µ¹Î ( Kim Young-Min ) 
¿ï»ê´ëÇб³ ÀÇ°ú´ëÇÐ º´¸®Çб³½Ç
ÃÖÇýÁ¤ ( Choi Hye-Jeong ) 
¿ï»ê´ëÇб³º´¿ø º´¸®°ú

Abstract


We present a case of mandibular involvement with Langerhans cell histiocytosis (LCH), diagnosed by ultrasound-guided aspiration and subsequently confirmed by incisional biopsy and immunohistochemistry in an eight-year-old boy. The cytologic findings included the presence of characteristic Langerhans cells of both mononucleate and multinucleate form. Diagnostic confirmation was obtained by immunopositivity for S-100 protein and CD1a of Langerhans histiocytes on paraffin-embedded sections obtained during incisional biopsy of the right mandibular area. By reporting a case of childhood LCH, we correlate the cytologic findings with histologic features and discuss the role of aspiration cytologic diagnosis in such a rare and cytomorphologically characteristic case.

Å°¿öµå

Histiocytosis;Langerhans cell;Mandible;Cytology;Child

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