A Case of Paraduodenal Pancreatitis and Immunohistochemical Analysis
권미정, 남은숙, 조성진, 신형식, 김주섭, 김두진,
소속 상세정보
권미정 ( Kwon Mi-Jung )
성균관대학교 의과대학 삼성서울병원 병리학교실
남은숙 ( Nam Eun-Sook )
한림대학교 의과대학 강동성심병원 병리학교실
조성진 ( Cho Seong-Jin )
한림대학교 의과대학 강동성심병원 병리학교실
신형식 ( Shin Hyung-Sik )
한림대학교 의과대학 강동성심병원 병리학교실
김주섭 ( Kim Joo-Seop )
한림대학교 의과대학 강동성심병원 외과학교실
김두진 ( Kim Doo-Jin )
한림대학교 의과대학 강동성심병원 외과학교실
KMID : 0357920100440020199
Abstract
Paraduodenal pancreatitis (PP) is a rare, distinct form of chronic pancreatitis, and it is related to alcohol abuse in middle-aged men. A 36-year-old man with a history of chronic recurrent pancreatitis for 4 years and alcohol abuse for 15 years presented with abdominal pain. Computed tomography revealed a multilocular cystic mass 3.2×3×3 cm in size and it was located within the muscular layer of the duodenal wall. The cysts were lined by a single layer of eosinophilic cuboidal epithelial cells that stained positively for mucin (MUC)1, MUC6, cytokeratin (CK)7 and CK19 and they stained negatively for MUC2, MUC5AC and CK5/6. Mild, chronic inflammatory reaction around the cystic wall, Brunner’s gland hyperplasia and several clusters of heterotopic pancreatic tissue were noted. We report here on a case of PP and we demonstrated that the pancreatitis was of pancreatic ductal cell origin according to the MUC and CK expression patterns we observed on the immunohistochemical analysis.
키워드
Pancreatitis;chronic;Pancreatic ducts;Cysts
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