Primary Malignant Melanoma of the Urinary Bladder - A Case Report -
이성학, 장은덕, 이은정, 강창석,
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이성학 ( Lee Sung-Hak )
가톨릭대학교 의과대학 병원병리학교실
장은덕 ( Chang Eun-Deok )
가톨릭대학교 의과대학 병원병리학교실
이은정 ( Lee Eun-Jung )
가톨릭대학교 의과대학 병원병리학교실
강창석 ( Kang Chang-Suk )
가톨릭대학교 의과대학 병원병리학교실
KMID : 0357920100440020216
Abstract
Primary malignant melanoma in the bladder is very rare, with only 18 cases having been currently reported. A 65-year-old male patient presented with a 5-month history of gross hematuria. On ultrasonography, an 8.1 × 6.1 cm mass was revealed on the bladder wall. A partial cystectomy was performed. Microscopically, the tumor was composed of atypical, pigmented melanocytes that were positive for S-100 protein and they were negative for human melanoma black-45. Although he underwent supportive therapy, an 8.7 × 5.9 cm mass occupying the prevesical space was noted on a follow-up computed tomography scan 4 months later. Two nodules of the left lower lung and multiple enlarged lymph nodes in the left external iliac chain were also revealed. The patient declined any further treatment. The histogenesis of primary bladder melanoma is uncertain, but an origin from neural crest cells has been proposed. The prognosis for patients with this tumor is still poor despite the availability of several therapeutic options.
키워드
Melanoma;Urinary bladder
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