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Fine Needle Aspiration Biopsy of a Myxoid Leiomyosarcoma with Epithelioid Features and It Metastasized to the Abdominal Wall - A Case Report -

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¸ÍÀ̼Ҡ( Maeng Lee-So ) 
°¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ÀÎõ¼º¸ðº´¿ø º´¿øº´¸®Çаú

äÇö¼® ( Chae Hiun-Suk ) 
°¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ÀÎõ¼º¸ðº´¿ø ³»°úÇб³½Ç
À̾ÈÈñ ( Lee An-Hi ) 
°¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ÀÎõ¼º¸ðº´¿ø º´¿øº´¸®Çаú
Á¤¿ë¾È ( Chung Yong-An ) 
°¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ÀÎõ¼º¸ðº´¿ø ¿µ»óÀÇÇаú
À̱³¿µ ( Lee Kyo-Young ) 
°¡Å縯´ëÇб³ ÀÇ°ú´ëÇÐ ÀÎõ¼º¸ðº´¿ø º´¿øº´¸®Çаú

Abstract


We present the cytologic findings observed in a fine needle aspiration biopsy specimen of a rare myxoid variant of leiomyosarcoma with epithelioid features and the tumor had metastasized to the abdominal wall. The aspirate showed hypercellularity in a hemorrhagic background. Some large 3-dimensional aggregates of spindle cells were observed. Each cell had a solitary ovoid-to-elongated nucleus with finely granulated chromatin, one or two small distinct nucleoli and an irregular nuclear membrane. There were irregular fascicles of spindle cells with cigar-shaped, blunt-ended nuclei admixed with inflammatory cells. Epithelioid cells with a rather narrow, dense cytoplasmic rim and a well-defined cell border were embedded in a myxoid matrix in a cord-like and cluster arrangement. The matrix appeared as a pale green substance with sharply defined edges. There were very few mitoses. These cytologic features were the same as those of a uterine myxoid leiomyosarcoma that was surgically excised 7 years ago, and immunohistochemical staining revealed the smooth muscle origin of the tumor.

Å°¿öµå

Cytology;Biopsy;fine-needle;Uterus;Leiomyosarcoma;Neoplasm metastasis

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