갑상샘 세침흡인세포검사 판독에 있어 베데스다 시스템의 적용
Application of Bethesda System for Reporting Thyroid Aspiration Cytology
이경지, 정창연, 이교영, 배자성, 임동준, 정소령,
소속 상세정보
이경지 ( Lee Kyung-Ji )
가톨릭대학교 의과대학 병원병리학교실
정창연 ( Jung Chang-Yeon )
가톨릭대학교 의과대학 병원병리학교실
이교영 ( Lee Kyo-Young )
가톨릭대학교 의과대학 병원병리학교실
배자성 ( Bae Ja-Seong )
가톨릭대학교 의과대학 외과학교실
임동준 ( Lim Dong-Jun )
가톨릭대학교 의과대학 내과학교실
정소령 ( Jung So-Lyung )
가톨릭대학교 의과대학 방사선과학교실
KMID : 0357920100440050521
Abstract
Background : The Bethesda classification system for reporting on thyroid fine-needle aspiration (FNA) cytology was recently proposed by the National Cancer Institute, USA. We aimed to report our experience with applying this system for thyroid FNA, with a focus on comparing it with the four categorical system.
Methods : We retrospectively reviewed the 4,966 thyroid FNAs that were performed at the Seoul St. Mary’s Hospital between October 2008 and September 2009. All the FNAs were classified according to the Bethesda system and the four tier system.
Results : The cytologic diagnoses of the Bethesda system included 10.0% unsatisfactory, 67.7% benign, 3.1% atypia of undetermined significance, 0.6% follicular neoplasm, 0.5% follicular neoplasm, Hurthle cell type, 5.1% suspicious for malignancy and 13.0% malignancy. Using four tier system, 10.1%, 67.6%, 9.3%, and 13% were diagnosed as unsatisfactory, negative for malignancy, atypical cells and malignancy, respectively. Of the 4,966 nodules, 905 were histologically confirmed. The specificity of the Bethesda system and the four tier system for diagnosing malignancy was 99.6% and 82.6%, respectively.
Conclusions : The Bethesda system can classify indeterminate thyroid nodules into more detailed categories and provide clinicians with useful information for management.
키워드
Biopsy; fine-needle; Thyroid neoplasms; Cytopathology; Diagnostic techniques and procedures
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