갑상샘 세침흡인검사의 액상세포검사(SurePathTM)와 고식적 도말검사의 소견 비교
Comparison of Liquid-based (SurePathTM) and Conventional Preparations in Thyroid Fine Needle Aspiration
채승완, 김선희, 박희대, 박운선, 조영혜, 강성희, 김동훈, 손진희,
소속 상세정보
채승완 ( Chae Seoung-Wan )
성균관대학교 의과대학 강북삼성병원 병리과학교실
김선희 ( Kim Sun-Hee )
성균관대학교 의과대학 강북삼성병원 병리과학교실
박희대 ( Park Hee-Dae )
성균관대학교 의과대학 강북삼성병원 병리과학교실
박운선 ( Park Woon-Sun )
성균관대학교 의과대학 강북삼성병원 병리과학교실
조영혜 ( Cho Young-Hye )
성균관대학교 의과대학 강북삼성병원 병리과학교실
강성희 ( Kang Sung-Hee )
성균관대학교 의과대학 강북삼성병원 병리과학교실
김동훈 ( Kim Dong-Hoon )
성균관대학교 의과대학 강북삼성병원 병리과학교실
손진희 ( Sohn Jin-Hee )
성균관대학교 의과대학 강북삼성병원 병리과학교실
KMID : 0357920100440060651
Abstract
Background : The aim of this study was to evaluate differences in cytologic findings between conventional preparation (CP) and SurePathTM liquid-based preparation (LBP) in thyroid fine needle aspiration (FNA).
Methods : We analyzed cytological features on a total of 182 thyroid FNAs (83 CP and 99 LBP) that were histologically confirmed as nodular hyperplasia (NH) or papillary carcinoma (PAC).
Results : LBP was superior in cellular preservation and cellularity than CP. Interestingly, in LBP, cellularity of NH was similarly high compared to that of PAC. The three-dimensional pattern was more prominent in LBP than in CP. The presence of follicle structures was more frequently found in LBP than in CP in the PAC group. Dispersed single cells in the background were more prominent in LBP than in CP. In the PAC group, contrast of the nuclear membrane was more distinctive in CP than in LBP.
Conclusions : In thyroid FNA, LBP is better for cellular preservation, cellularity, background and nuclear detail than CP. However, some features in LBP such as high cellularity in NH, prominent dispersed single cells, and frequent follicle patterns were unfamiliar findings in CP. Hence, we should be aware of these cytomorphologic features in LBP to make a proper diagnosis.
키워드
Thyroid gland; Biopsy; fine-needle; SurePath
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