A Case of Ovarian Microinvasive Mucinous Carcinoma and Co-existent Angiosarcoma
허진형, 이윤희, 김광일, 김태현, 강혜윤, 안희정, 윤보성, 성석주, 박현, 김지영,
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허진형 ( Heo Jin-Hyung )
CHA University School of Medicine Department of Pathology
이윤희 ( Lee Yoon-Hee )
CHA University School of Medicine Department of Pathology
김광일 ( Kim Gwang-Il )
CHA University School of Medicine Department of Pathology
김태현 ( Kim Tae-Heon )
CHA University School of Medicine Department of Pathology
강혜윤 ( Kang Hae-Youn )
CHA University School of Medicine Department of Pathology
안희정 ( An Hee-Jung )
CHA University School of Medicine Department of Pathology
윤보성 ( Yoon Bo-Sung )
CHA University School of Medicine Department of Obstetric and Gynecology
성석주 ( Seong Seok-Ju )
CHA University School of Medicine Department of Obstetric and Gynecology
박현 ( Park Hyun )
CHA University School of Medicine Department of Obstetric and Gynecology
김지영 ( Kim Ji-Young )
CHA University School of Medicine Department of Pathology
KMID : 0357920110450010096
Abstract
Primary ovarian angiosarcoma is very rare with only 27 cases reported so far in the medical literature. We report here on a rare case of ovarian microinvasive mucinous carcinoma that was coexistent with angiosarcoma in a 54-year-old woman. The tumor was a 26×19×10 cm-sized multilocular cystic mass with a 4×3 cm-sized solid hematoma-like nodule in the center. Microscopically, it was composed mostly of mucinous tumor of various grades from borderline to microinvasive carcinoma. The hematoma-like area turned out to be an angiosarcoma, composed of pleomorphic cells that formed slit-like spaces, spindle cells that formed short fascicles and anastomosing vascular channels with atypical endothelial cells. All these cells were positive for CD31, CD34 and factor VIII-related antigen. The patient developed peritoneal and pleural metastases, which were angiosarcoma and mucinous carcinoma, respectively. We believe this case is only the fourth example of an ovarian collision tumor of angiosarcoma and surface epithelial tumor.
키워드
Hemangiosarcoma; Cystadenocarcinoma; mucinous; Ovary
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