Langerhans Cell Sarcoma Arising in a Lymph Node - A Case Report and Review of the Literature -
강동욱, 손현진, 백태화, 이혜경, 허주령, 김주헌, 박미자,
소속 상세정보
강동욱 ( Kang Dong-Wook )
Eulji University School of Medicine Department of Pathology
손현진 ( Son Hyun-Jin )
Eulji University School of Medicine Department of Pathology
백태화 ( Baek Tae-Hwa )
Eulji University School of Medicine Department of Pathology
이혜경 ( Lee Hye-Kyung )
Eulji University School of Medicine Department of Pathology
허주령 ( Huh Joo-Ryung )
University of Ulsan College of Medicine Department of Pathology
김주헌 ( Kim Joo-Heon )
Eulji University School of Medicine Department of Pathology
박미자 ( Park Mee-Ja )
Eulji University School of Medicine Department of Pathology
KMID : 0357920110450010101
Abstract
We report a case of Langerhans cell sarcoma presented as a solitary mass in the left supraclavicular area in a 31-year-old woman. Computed tomography revealed a relatively well-defined and lightly enhancing mass in the left supraclavicular area, measuring 5.5×4.5×3.2 cm. Excision was subsequently performed. Microscopically, the specimen consisted of an enlarged and partially effaced lymph node. Nests of different size composed of atypical tumor cells were located in the paracortex and the medulla of the lymph node. The tumor cells exhibited abundant eosinophilic or clear cytoplasm and displayed marked nuclear atypia and increased mitotic figures. Infiltration of many eosinophils was identified in the periphery and between the tumor cells. The tumor cells were reactive for CD1a and S100 protein. Ultrastructually, they were found to have Birbeck granules in the cytoplasm.
키워드
Langerhans cell sarcoma; Lymph nodes; CD1a antigen
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