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Fine Needle Aspiration Cytologic Findings of Angiosarcoma- Report of Two Cases -

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Ji Jin-Xian, ÁÖ¿µÃ¤, ±è·ç½Ã¾Æ, ÃÖ¼®Áø, ¹ÚÀμ­, ÇÑÁö¿µ, ±èÁعÌ, ±è±ÔÈ£, ¼ÛÁÖ¿µ,
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 ( Ji Jin-Xian ) 
Inha University College of Medicine Department of Pathology

ÁÖ¿µÃ¤ ( Chu Young-Chae ) 
Inha University College of Medicine Department of Pathology
±è·ç½Ã¾Æ ( Kim Lucia ) 
Inha University College of Medicine Department of Pathology
ÃÖ¼®Áø ( Choi Suk-Jin ) 
Inha University College of Medicine Department of Pathology
¹ÚÀμ­ ( Park In-Suh ) 
Inha University College of Medicine Department of Pathology
ÇÑÁö¿µ ( Han Jee-Young ) 
Inha University College of Medicine Department of Pathology
±èÁع̠( Kim Joon-Mee ) 
Inha University College of Medicine Department of Pathology
±è±ÔÈ£ ( Kim Kyu-Ho ) 
Inha University College of Medicine Department of Pathology
¼ÛÁÖ¿µ ( Song Ju-Young ) 
Inha University College of Medicine Department of Pathology

Abstract


Angiosarcoma is a rare malignant vascular neoplasm which can arise in any part of the body. Specific recognition of this neoplasm in cytological specimens is difficult in the absence of an ancillary method. Herein, we present the cytologic findings of two cases of angiosarcomas diagnosed on fine needle aspiration cytology. One case is a recurred angiosarcoma in the left chest wall and the other case is a lymphedema-associated angiosarcoma in the left lower leg. The cytologic findings of both cases are similar. Cytologic features that identified this neoplasm as an angiosarcoma included arborizing microtissue fragments, irregular anastomosing vascular spaces lined by atypical cells, microacini, intracytoplasmic lumen, and intracellular red blood cells, marked cell discohesiveness, spindle to ovoid, irregular, hyperchromatic nuclei, and elongated cytoplasmic processes with indistinct borders. This report emphasizes that when aspiration smears show vasoformative features in a bloody background, angiosarcoma should be included in the differential diagnosis.

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Angiosarcoma; Fine needle aspiration cytology

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