Apocrine Carcinoma of the Axilla with Predominant Signet Ring Cell Features - A Case Report -
김진아, 김태은, 이아원, 최영진, 이교영, 정은선,
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김진아 ( Kim Jean-A )
Catholic University College of Medicine Department of Hospital Pathology
김태은 ( Kim Tae-Eun )
Catholic University College of Medicine Department of Hospital Pathology
이아원 ( Lee Ah-Won )
Catholic University College of Medicine Department of Hospital Pathology
최영진 ( Choi Yeong-Jin )
Catholic University College of Medicine Department of Hospital Pathology
이교영 ( Lee Kyo-Young )
Catholic University College of Medicine Department of Hospital Pathology
정은선 ( Jung Eun-Sun )
Catholic University College of Medicine Department of Hospital Pathology
KMID : 0357920110450030326
Abstract
Apocrine carcinoma arising from the apocrine sweat glands is a rare cutaneous malignant tumor which occurs predominantly in the axilla of elderly individuals. The typical histologic features of apocrine carcinoma is within a well developed glandular lumina with abundant eosinophilic cytoplasm and evidence of decapitation secretion. In rare instances, predominant signet ring cell features in apocrine carcinoma has been reported. We experienced a case that occured in the right axilla of a 59-year-old. Histopathologic examination showed a solid tumor that extended from the upper dermis into the subcutis, with a delicate infiltrate of epithelial cells. The cells had granular amphophilic cytoplasm, predominantly showed distinct signet ring cell morphology, and were strongly positive for epithelial mucin. Both lysozyme and gross cystic disease fluid protein-15 were identified in the tumor cells. We diagnosed this to be a case of primary signet ring cell apocrine carcinoma of the axilla after several immunohistochemical and clinical evaluations.
키워드
Apocrine glands; Carcinoma; signet ring cell; Axilla
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