Primary Hepatic Neuroblastoma - A Case Report -
Jung Geun-Young, 김지헌,
소속 상세정보
( Jung Geun-Young )
University of Ulsan College of Medicine Department of Pathology
김지헌 ( Kim Ji-Hun )
University of Ulsan College of Medicine Department of Pathology
KMID : 0357920110450040423
Abstract
Neuroblastoma is a malignant tumor of primordial neural crest origin. It usually develops along the sympathetic nervous system, such as the adrenal glands or paramedian sympathetic chain and metastasizes to the liver most frequently. However, a primary hepatic neuroblastoma has not been reported yet. Here, we report a case of 29-year-old woman who presented with a solitary hepatic mass. Grossly, the mass was large, creamy, rubbery firm, and showed focal hemorrhage and central cavitation. Microscopically, the tumor cells were arranged in small nests of spindle to ovoid cells with abundant neuropil. The neuroblastic nature of the tumor was confirmed by immunohistochemistry and electron microscopy. No extrahepatic mass was found, despite a thorough systemic survey such as chest and abdominopelvic computed tomography (CT) scans and a whole body positron emission tomography-CT study. To the best of our knowledge, this is the first report of a bona fide primary hepatic neuroblastoma.
키워드
Neuroblastoma;Liver neoplasms;Microscopy;electron;Adult
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