자궁경부 악성 림프종의 액상세포검사(SurepathTM) 도말 소견 -3 증례보고-
Liquid-Based Pap Smear Findings of Uterine Cervical Lymphoma - Three Cases Report -
김지영, 김혜선, 홍성란, 전이경, 김희숙,
소속 상세정보
김지영 ( Kim Ji-Young )
관동대학교 의과대학 제일병원 병리과
김혜선 ( Kim Hye-Sun )
관동대학교 의과대학 제일병원 병리과
홍성란 ( Hong Sung-Ran )
관동대학교 의과대학 제일병원 병리과
전이경 ( Chun Yi-Kyeong )
관동대학교 의과대학 제일병원 병리과
김희숙 ( Kim Hy-Sook )
관동대학교 의과대학 제일병원 병리과
KMID : 0357920110450040437
Abstract
Malignant lymphoma of the uterine cervix is rarely diagnosed by cytology because it presents as a subepithelial mass. We report three cases of diffuse large B-cell lymphoma in the uterine cervix with a description of liquid-based pap smear (LBP) findings. All patients were presented with cervical masses, but a suspicion of malignant lymphoma was made in only one case by preoperative LBP. The LBP of two cases showed several atypical lymphoid cells in a clear background. The other case revealed numerous atypical lymphoid cells in a necrotic background. Most tumor cells had an increased N/C ratio, round but focally irregular nuclei, coarse chromatin, and prominent nucleoli. Nuclear blebing, dimpling, and multi-lobulation were also found. Diagnosis of malignant lymphoma by LBP is usually more difficult than by conventional techniques, because of a sparse numbers of cells and the lack of necrotic background. However, well preserved morphological features and a better resolution of nuclear details could be the benefits of LBP.
키워드
Cervix;Lymphoma;Liquid-based cytology;Surepath
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