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Type and lncidence of Soft Tissue Sarcomas in Korea: 2001-2007

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ÃÖ°æ¿î ( Choi Kyung-Un ) 
Pusan National University College of Medicine Department of Pathology

°­ÇýÀ± ( Kang Hae-Youn ) 
CHA University Bundang CHA Hospital Department of Pathology
±¸Çý¼ö ( Koo Hea-Soo ) 
Ewha Womans University College of Medicine Department of Pathology
±Ç¹Ì¼± ( Kwon Mi-Seon ) 
Dankook University Hospital Department of Pathology
±èµ¿ÈÆ ( Kim Dong-Hoon ) 
Sungkyunkwan University School of Medicine Department of Pathology
±è¹ÌÁ¤ ( Kim Mi-Jung ) 
Seoul Asan Medical Center Department of Pathology
±è¼öÁø ( Kim Su-Jin ) 
Dong-A University College of Medicine Department of Pathology
±è¿µ½Ç ( Kim Young-Sil ) 
Jeju National University Hospital Department of Pathology
±èöȯ ( Kim Chul-Hwan ) 
Korea University College of Medicine Anam Hospital Department of Pathology
¹Ú¿ë±¸ ( Park Yong-Koo ) 
Kyung Hee University School of Medicine Department of Pathology
¹ÚÇý¸² ( Park Hye-Rim ) 
Hallym University Medical Center Department of Pathology
¹é½Â»ï ( Paik Seung-Sam ) 
Hanyang University College of Medicine Department of Pathology
À¯Áø¿µ ( Yoo Jin-Young ) 
St. Vincent Hospital Department of Pathology
À̾ÈÈñ ( Lee An-Hi ) 
Incheon St. Mary¡¯s Hospital Department of Pathology
ÀÌÁ¦Çõ ( Lee Jae-Hyuk ) 
Chonnam National University Hwasun Hospital Department of Pathology
ÀÌÇý°æ ( Lee Hye-Kyung ) 
Eulji University School of Medicine Department of Pathology
Àå±ÔÀ± ( Jang Kyu-Yun ) 
Chonbuk National University Medical School Department of Pathology
ÁÖ¿µÃ¤ ( Chu Young-Chae ) 
Inha University College of Medicine Department of Pathology
ÃÖÁØÇõ ( Choi Joon-Hyuk ) 
Yeungnam University College of Medicine Department of Pathology

Abstract


Background : The Korean Bone and Soft Tissue Pathology Study Group of the Korean Society of Pathologists conducted a nationwide retrospective analysis of soft tissue sarcoma (STS) to provide the clinicopathologic characteristics of STS within the population of the Republic of Korea.

Methods : The cases of STS were collected during a 7-year period (2001-2007) from 19 institutes in Korea. All cases were classified according to the histologic criteria proposed by the World Health Organization. Clinicopathologic data were reviewed.

Results : Data from 722 patients (median age, 50 years) were collected. Data showed a slight male predominance. The most frequent types of STS in decreasing order were liposarcoma, malignant fibrous histiocytoma, leiomyosarcoma, and synovial sarcoma. STS occurred throughout the body, although approximately half (47.8%) were located in the extremities. The majority of STS was histologically classified as high grade with a large tumor size (>5 cm). The overall survival rate for the patients was 76.3% (median follow-up time, 26 months; range, 1 to 89 months). Histologic grade, tumor size, American Joint Committee on Cancer stage, tumor site, and resection status were prognostic. Significant independent adverse prognostic factors were large tumor size (>5 cm) and tumor site other than extremities.

Conclusions : We reported the distribution and characteristics of STS in the Republic of Korea.

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Sarcoma; Korea; Incidence; Type; Prognosis

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