A Cutaneous Myoepithelial Carcinoma Arising in a Papillary Eccrine Adenoma
정지한, 임소영, 강석진, 김경문, 한기택, 유진영, 강창석,
소속 상세정보
정지한 ( Jung Ji-Han )
Catholic University School of Medicine Department of Hospital Pathology
임소영 ( Im So-Young )
Catholic University College of Medicine Department of Hospital Pathology
강석진 ( Kang Seok-Jin )
Catholic University College of Medicine Department of Hospital Pathology
김경문 ( Kim Gyong-Moon )
Catholic University College of Medicine Department of Dermatology
한기택 ( Han Ki-Taik )
Catholic University College of Medicine Department of Plastic and Reconstructive Surgery
유진영 ( Yoo Jin-Young )
Catholic University College of Medicine Department of Hospital Pathology
강창석 ( Kang Chang-Suk )
Catholic University College of Medicine Department of Hospital Pathology
KMID : 0357920110450060644
Abstract
Cutaneous myoepithelial neoplasms and papillary eccrine adenomas (PEA) are rare conditions. Malignant tumors within a PEA are even rarer, with only one case reported to date. Herein, we present an extremely rare case of a cutaneous myoepithelial carcinoma arising in a PEA in a 70- year-old man presenting a solid mass in the left buttock. Histopathologically, most of the resected tumor revealed features consistent with the diagnosis of PEA. Some small nests and nodules were intermixed with the PEA and were present adjacent to the PEA. The tumor cells of nests and nodules showed ovoid to spindle shaped nuclei and slightly eosinophilic cytoplasm. Immunohistochemically, they were positive for both epithelial and myogenic markers, consistent with myoepithelioma. An inguinal lymph node with a metastatic lesion showed the same findings of myoepithelioma despite inconspicuous atypia. Our case showed malignant transformation of the myoepithelial cells at the outermost layers of the PEA.
키워드
Skin; Myoepithelial carcinoma; Papillary eccrine adenoma
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