A Soft Tissue Perineurioma and a Hybrid Tumor of Perineurioma and Schwannoma
박지영, 박남조, 김상표, 권건영, 이상숙,
소속 상세정보
박지영 ( Park Ji-Young )
Keimyung University College of Medicine Department of Pathology
박남조 ( Park Nam-Jo )
Keimyung University College of Medicine Department of Pathology
김상표 ( Kim Sang-Pyo )
Keimyung University College of Medicine Department of Pathology
권건영 ( Kwon Kun-Young )
Keimyung University College of Medicine Department of Pathology
이상숙 ( Lee Sang-Sook )
Keimyung University College of Medicine Department of Pathology
KMID : 0357920120460010075
Abstract
Perineuriomas are composed of differentiated perineurial cells. Perineuriomas have been recently recognized by the immunoreactivity for epithelial membrane antigen (EMA). Microscopically, perineuriomas show proliferation of spindle cells with wavy nuclei and delicate elongated bipolar cytoplasmic processes. The tumor cells are usually negative for the S-100 protein. Ultrastructurally, perineurial cells reveal slender, nontapered processes containing pinocytic vesicles and discontinuous basal lamina. Interestingly, hybrid tumors of benign peripheral nerve sheath tumor (PNST) have been recently reported by using immunohistochemical and ultrastructural investigations. Herein, we report a case of soft tissue perineurioma arising in the skin of a 56-year-old female; another case of a hybrid tumor of perineurioma and schwannoma in the posterior mediastinum occurred in a 53-year-old male, which is the first case of the hybrid PNST tumor reported in Korea.
키워드
Soft tissue; Perineurioma; Nerve sheath neoplasms; Hybrid tumor
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