Endoscopic Ultrasound-Guided Fine Needle Aspiration Cytology Diagnosis of Solid Pseudopapillary Neoplasm: Three Case Reports with Review of Literature
송준선, 유종우, 권영미, 홍은경,
소속 상세정보
송준선 ( Song Joon-Seon )
University of Ulsan College of Medicine Department of Pathology
유종우 ( Yoo Chong-Woo )
National Cancer Center Center for Liver Cancer Department of Pathology
권영미 ( Kwon Young-Mee )
National Cancer Center Center for Liver Cancer Department of Pathology
홍은경 ( Hong Eun-Kyung )
National Cancer Center Center for Liver Cancer Department of Pathology
KMID : 0357920120460020399
Abstract
Solid pseudopapillary neoplasm of the pancreas (SPN) is relatively rare and it occurs almost exclusively in women. We recently experienced three cases of SPN diagnosed by endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA). These three cases were two male and one female patient whose age was 29, 37, and 44 years old. Radiological diagnosis was pancreatic endocrine tumor (PEN) showing solid with a heterogenous echogenicity. EUS-FNA cytology specimens consisted of single cells and aggregates of uniform cells, forming microadenoid structures, branching, papillary clusters with delicate fibrovascular cores. In conclusion, a single diagnosis of SPN based on clinical and radiological findings would be risky because there is a possibility of it being misdiagnosed as PEN or other malignancies. An EUS-FNA is therefore essential for establishing the diagnosis. In addition, the pathologists should recognize the characteristic cytologic findings with immunoprofiles of SPN to prevent misdiagnosis of SPN.
키워드
Solid pseudopapillary neoplasm; Endoscopic ultrasound-guided fine needle aspiration; Cytology
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