Metastatic Carcinomas to the Oral Cavity and Oropharynx
신수진, 노종렬, 최승호, 남순열, 김상윤, 김성배, 이상욱, 조경자,
소속 상세정보
신수진 ( Shin Su-Jin )
University of Ulsan College of Medicine Department of Pathology
노종렬 ( Roh Jong-Lyel )
University of Ulsan College of Medicine Asan Medical Center Department of Head and Neck Surgery
최승호 ( Choi Seung-Ho )
University of Ulsan College of Medicine Asan Medical Center Department of Head and Neck Surgery
남순열 ( Nam Soon-Yuhl )
University of Ulsan College of Medicine Asan Medical Center Department of Head and Neck Surgery
김상윤 ( Kim Sang-Yoon )
University of Ulsan College of Medicine Asan Medical Center Department of Head and Neck Surgery
김성배 ( Kim Sung-Bae )
University of Ulsan College of Medicine Asan Medical Center Department of Medical Oncology
이상욱 ( Lee Sang-Wook )
University of Ulsan College of Medicine Department of Radiation Oncology
조경자 ( Cho Kyung-Ja )
University of Ulsan College of Medicine Department of Pathology
KMID : 0357920120460030266
Abstract
Background : Metastases to the oral/oropharynx are very rare and their diagnosis is challenging.
Methods : We reviewed pathologic data for malignant tumors of the oral/oropharynx that were diagnosed at the Asan Medical Center, Seoul, Korea from 1995 until 2010.
Results : Twenty-nine cases of oral/oropharyngeal metastases were retrieved, comprising 2.0% of 1,445 malignancies. The most common primary sites were the liver and lung, followed by the stomach, colon, breast, prostate, and kidney. The gingiva was the most common metastatic site, followed by the tonsil/pillar, mandible, tongue, tongue base, palate mucosa, mouth floor, and buccal mucosa. Intervals between detection of primary tumors and metastases were variable, from -1 month to 104 months. Ten patients with lung (7 cases), liver, stomach, and kidney carcinomas manifested with oral/oropharyngeal metastases as the first sign of systemic metastases. The majority of patients had died within one year of the onset of an oral/oropharyngeal metastasis, but exceptionally long-lived cases were also present. The survival periods of patients with lung cancers were longer than those of patients with non-pulmonary tumors.
Conclusions : An awareness of the incidence, common primary sites, metastatic subsites, and metastatic courses or patterns of oral/oropharyngeal metastases is helpful in the diagnosis of metastatic carcinomas.
키워드
Mouth; Neoplasms; Metastasis; Oropharynx
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