Plexiform Angiomyxoid Myofibroblastic Tumor of the Stomach: Report of Two Cases and Review of the Literature
강영란, 정원경, 도인구, 이의진, Lee Min-Hyeong, 김경미, 최종상,
소속 상세정보
강영란 ( Kang Young-Ran )
Korea University College of Medicine Department of Pathology
정원경 ( Jung Won-Kyung )
Korea University College of Medicine Department of Pathology
도인구 ( Do In-Gu )
Sungkyunkwan University School of Medicine Samsung Medical Center Department of Pathology
이의진 ( Lee Eui-Jin )
Sungkyunkwan University School of Medicine Samsung Medical Center Department of Pathology
( Lee Min-Hyeong )
USA Cornell University Department of Biology
김경미 ( Kim Kyoung-Mee )
Sungkyunkwan University School of Medicine Department of Pathology
최종상 ( Choi Jong-Sang )
Korea University College of Medicine Department of Pathology
KMID : 0357920120460030292
Abstract
Plexiform angiomyxoid myofibroblastic tumor (PAMT) of the stomach is a recently recognized entity. Because of its rarity, only 22 cases have been reported in the English-language literature and most of these are single case reports. We report two cases of gastric PAMT. The tumor cells were bland and plexiform arranged in a myxoid stroma, which was positive for alcian blue. Immunohistochemically, the tumor cells were positive for smooth muscle actin, but negative for c-kit, CD34, desmin, S-100 protein, epithelial membrane antigen, neurofilament, and protein kinase C-theta. Mutation analyses for exon 9, 11, 13, and 17 of KIT genes and 12, 14, and 18 of the platelet-derived growth factor receptor alpha (PDGFRA) genes were performed and the tumors were wild-type for mutation.
키워드
Angiomyxoid; Stomach; Myofibroblasts; Plexiform; Prognosis; Review
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