Osteoclast-like Giant Cell Tumor of Parotid Gland with a Carcinomatous Component: A Case Report
양정욱, 김현철, 이정희, 이종실, 김동철, 송대현, 김진평, 고경혁,
소속 상세정보
양정욱 ( Yang Jung-Wook )
Gyeongsang National University School of Medicine Department of Pathology
김현철 ( Kim Hyeon-Cheol )
Gyeongsang National University School of Medicine Department of Pathology
이정희 ( Lee Jeong-Hee )
Gyeongsang National University School of Medicine Department of Pathology
이종실 ( Lee Jong-Sil )
Gyeongsang National University School of Medicine Department of Pathology
김동철 ( Kim Dong-Chul )
Gyeongsang National University School of Medicine Department of Pathology
송대현 ( Song Dae-Hyun )
Gyeongsang National University School of Medicine Department of Pathology
김진평 ( Kim Jin-Pyeong )
Gyeongsang National University College of Medicine Department of Otorhinolaryngology
고경혁 ( Ko Gyung-Hyuck )
Gyeongsang National University School of Medicine Department of Pathology
KMID : 0357920120460030297
Abstract
The giant cell tumor of the salivary gland is very rare, and 20 cases have been reported in the English-language literature. We report an additional case. A 57-year old man had noticed a mass in the right parotid area for several weeks. The diagnosis using aspiration cytology was a giant cell tumor possibly with a carcinomatous component. Superficial parotidectomy was carried out. The resected parotid gland contained a 1.8 cm-sized well-circumscribed brownish tumor. Histologically the tumor consisted of evenly distributed osteoclast-like giant cells, mononuclear cells and two small foci of a carcinomatous component. The osteoclast-like giant cells and mononuclear cells were positive for vimentin and CD68, and the carcinomatous component was positive for cytokeratin and epithelial membrane antigen. There was no metastatic lesion in the cervical lymph nodes. We believe this is the first case in Korea of an osteoclast-like giant cell tumor of the parotid gland.
키워드
Giant cell tumors; Salivary glands
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