Cytologic Findings of Thyroid Carcinoma Showing Thymus-like Differentiation: A Case Report
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Àå¼±Èñ ( Chang Sun-Hee )
Inje University Ilsan Paik Hospital Department of Pathology
ÁÖ¹Ì ( Joo Mee )
Inje University Ilsan Paik Hospital Department of Pathology
±èÇѼº ( Kim Han-Seong )
Inje University Ilsan Paik Hospital Department of Pathology
KMID : 0357920120460030302
Abstract
Carcinoma showing thymus-like differentiation (CASTLE) is a rare carcinoma of the thyroid or adjacent soft tissue of the neck with a histologic resemblance to thymic epithelial tumors. Although the fine-needle aspiration (FNA) plays a central role in the initial evaluation of thyroid nodules, few reports about the cytologic findings of CASTLE have been found according to a review of literatures. We report cytologic findings of a case of CASTLE. A 34-year-old woman presented with a 2-month history of sore throat. The FNA showed that the smear was composed of three dimensional clusters and sheets. The tumor cells were round to ovoid with high nuclear:cytoplasmic ratios. The nuclei were vesicular with small nucleoli. There were some tumor cells showing keratinization. Some lymphocytes were found on the background and within clusters. The presence of poorly-differentiated tumor cells with a focal keratinization and a lymphocytic background on the FNA is suggestive of CASTLE.
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Thymoma; Thymus gland; Thyroid gland; Biopsy; fine-needle; Cytodiagnosis
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