Primary Endometrial Squamous Cell Carcinoma: A Case Report and Review of Relevant Literature on Korean Women
이성종, 최현주,
소속 상세정보
이성종 ( Lee Sung-Jong )
Catholic University College of Medicine Department of Obstetrics and Gynecology
최현주 ( Choi Hyun-Joo )
Catholic University School of Medicine Department of Hospital Pathology
KMID : 0357920120460040395
Abstract
Primary endometrial squamous cell carcinoma (PESCC) is an extremely rare tumor with unclear pathogenesis. A 54-year-old postmenopausal woman presented with a 6-month history of vaginal bleeding. The patient was provisionally diagnosed with uterine submucosal leiomyoma. This was followed by total hysterectomy with a bilateral salpingo-oophorectomy under the laparoscopic guidance. Histopathologically, the tumor was PESCC which was accompanied by a lack of the tumor in the uterine cervix. The tumor showed positive immunoreactivity for p16INK4a. But there was no evidence of human papillomavirus (HPV) on in situ hybridization and HPV DNA chip analysis. We also present a review of the relevant literature on Korean women.
키워드
Endometrium; Carcinoma; squamous cell; Human papillomavirus; In situ hybridization; Genes; p16
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