Ghost Cell Odontogenic Carcinoma Arising from Calcifying Cystic Odontogenic Tumor: A Case Report
Zhu Zhi-Yu, Chu Zhi-Gang, Chen Yu, Zhang Wei-Ping, Lv Di, Geng Ning, Yang Ming-Zhong,
소속 상세정보
( Zhu Zhi-Yu )
Sichuan University West China Hospital of Stomatology Department of Pathology
( Chu Zhi-Gang )
Sichuan University West China Hospital of Stomatology Department of Radiology
( Chen Yu )
Sichuan University West China Hospital of Stomatology Department of Pathology
( Zhang Wei-Ping )
Sichuan University West China Hospital of Stomatology Department of Pathology
( Lv Di )
Sichuan University West China Hospital of Stomatology Department of Pathology
( Geng Ning )
Sichuan University West China Hospital of Stomatology Department of Pathology
( Yang Ming-Zhong )
Sichuan University West China Hospital of Stomatology Department of Pathology
KMID : 0357920120460050478
Abstract
Ghost cell odontogenic carcinoma (GCOC) is an exceptionally rare and malignant odontogenic tumor with aggressive growth characteristics. We describe a case of GCOC which was considerably derived from a previously resected calcifying cystic odontogenic tumor (CCOT). Cellular atypia, mitotic activity, Ki-67 labeling index and matrix metalloprotease-9 positive expression rate were all increased in the currently resected specimen compared to the initial one. This is a rare case of malignant transformation of CCOT to GCOC with respect to its histopathological and immunohistochemical findings.
키워드
Ghost cell odontogenic carcinoma; Calcifying cystic odontogenic tumor
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