Castleman’s Disease of the Renal Sinus Presenting as a Urothelial Malignancy: A Brief Case Report
장세민, 한호림, 장기석, 전영진, 이춘용, 백승삼,
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장세민 ( Jang Se-Min )
Hanyang University College of Medicine Department of Pathology
한호림 ( Han Hu-Lin )
Hanyang University College of Medicine Department of Pathology
장기석 ( Jang Ki-Seok )
Hanyang University College of Medicine Department of Pathology
전영진 ( Jun Young-Jin )
Hanyang University College of Medicine Department of Pathology
이춘용 ( Lee Tchun-Yong )
Hanyang University College of Medicine Department of Urology
백승삼 ( Paik Seung-Sam )
Hanyang University College of Medicine Department of Pathology
KMID : 0357920120460050503
Abstract
Castleman’s disease is a rare benign lymphoproliferative disorder that frequently affects lymph nodes of the mediastinal thorax and the neck. It very rarely affects the renal sinus. We report a case of Castleman’s disease arising in the renal sinus in a 64-year-old man. The patient visited the hospital with the chief complaint of hematuria. Abdominal computed tomography revealed a homogeneous mass in the sinus of the left kidney, radiologically interpreted as a malignant urothelial tumor. Subsequently, nephroureterectomy was performed, after which microscopic examination of the specimen revealed a diffuse lymphoproliferative lesion with reactive lymphoid follicles of various sizes and prominent plasma cell infiltration of interfollicular spaces, highlighted by immunohistochemical staining for CD138. The lesion was diagnosed as Castleman’s disease of the plasma cell type. Although preoperative diagnosis of Castleman’s disease is difficult and the incidence is exceedingly rare, it should be considered in the differential diagnosis of renal sinus tumors.
키워드
Giant lymph node hyperplasia; Plasma cell type; Renal sinus; Urothelial malignancy; Kidney
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