Pulmonary Calciphylaxis Associated with Acute Respiratory and Renal Failure Due to Cryptogenic Hypercalcemia: An Autopsy Case Report
김나래, 서진원, 임영환, Ham Hyoung-Suk, 허우성, 한정호,
소속 상세정보
김나래 ( Kim Na-Rae )
Gachon University Gil Medical Center Department of Pathology
서진원 ( Seo Jin-Won )
Hallym University Sacred Heart Hospital Department of Pathology
임영환 ( Lim Young-Hwan )
Sungkyunkwan University School of Medicine Samsung Medical Center Department of Internal Medicine
( Ham Hyoung-Suk )
Sungkyunkwan University School of Medicine Samsung Medical Center Department of Internal Medicine
허우성 ( Huh Woo-Seong )
Sungkyunkwan University School of Medicine Samsung Medical Center Department of Internal Medicine
한정호 ( Han Joung-Ho )
Sungkyunkwan University School of Medicine Samsung Medical Center Department of Pathology
KMID : 0357920120460060601
Abstract
Metastatic calcification is rare; it is found during autopsy in patients who underwent hemodialysis. Diffuse calcium precipitation of small and medium-sized cutaneous vessels, known as calciphylaxis, can result in progressive tissue necrosis secondary to vascular calcification. This condition most commonly involves the skin; however, a rare occurrence of visceral calciphylaxis has been reported. Here we report on an autopsy case. Despite a thorough evaluation, and even performing an autopsy, the underlying cause of acute-onset hypercalcemia, resulting in the production of pulmonary calciphylaxis and metastatic renal calcification associated with acute respiratory and renal failure, could not be determined. Metastatic calcification often lacks specific symptoms, and the degree of calcification is a marker of the severity and chronicity of the disease. This unusual autopsy case emphasizes the importance of rapidly progressing visceral calciphylaxis, as well as its early detection.
키워드
Calcification; Hypercalcemia; Calciphylaxis
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