Peripheral Primitive Neuroectodermal Tumor with Osseous Component of the Small Bowel Mesentery: A Case Study
김준미, 주영채, 최창환, 김루시아, 최석진, 박인서, 한지영, 김경래, 최윤라, 김태은,
소속 상세정보
김준미 ( Kim Joon-Mee )
Inha University Hospital Department of Pathology
주영채 ( Chu Young-Chae )
Inha University Hospital Department of Pathology
최창환 ( Choi Chang-Hwan )
Inha University Hospital Department of Pathology
김루시아 ( Kim Lucia )
Inha University Hospital Department of Pathology
최석진 ( Choi Suk-Jin )
Inha University Hospital Department of Pathology
박인서 ( Park In-Suh )
Inha University Hospital Department of Pathology
한지영 ( Han Jee-Young )
Inha University Hospital Department of Pathology
김경래 ( Kim Kyung-Rae )
Inha University Hospital Department of Surgery
최윤라 ( Choi Yoon-La )
Sungkyunkwan University School of Medicine Samsung Medical Center Department of Pathology
김태은 ( Kim Tae-Eun )
Gachon University of Medicine and Science Department of Pathology
KMID : 0357920130470010077
Abstract
A case of peripheral primitive neuroectodermal tumor of the small bowel mesentery with osseous component is reported. A 23-year-old man was admitted to our hospital because of acute severe abdominal pain. Abdominal computed tomography revealed a large solid and cystic, oval shaped mass, measuring 11.0×6.0 cm in the pelvic cavity. Histologically the resected lesion consisted of sheets of undifferentiated small round cells forming Homer-Wright rosettes and perivascular pseudorosettes, and showed areas of osteoid and bone formation. Immunohistochemical studies revealed that tumor cells expressed positivity against CD99 (MIC2), CD57, neuron-specific enolase, and vimentin. Fluorescence in situ hybridization study revealed Ewing sarcoma breakpoint region 1 (EWSR1) gene rearrangement on chromosome 22q12. To the authors’ knowledge this is the first documentation of a peripheral neuroectodermal tumor with osteoid and bone formation of the small bowel mesentery.
키워드
Neuroectodermal tumor; primitive; peripheral; Intestine; small; Osteogenesis; Metaplasia; EWSR1
원문 및 링크아웃 정보
등재저널 정보